Research & Innovation

Advancing Precision Stroke Medicine

Precision Medicine

Counterfactual ML models for individualized EVT decisions.

PMID: 41603297

AI-Enabled Stroke Systems

AI triage across 60-spoke network; LUCID decision support.

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Clinical Trials

Primary Manager & Co-PI of the DUSK Trial — a multicenter RCT for DMVO stroke thrombectomy.

DUSK Trial

Patents & Devices

Intracranial stent (IBAS); AI-powered stroke decision support.

Evidence Synthesis

VERITAS (Lancet), ATLAS-ER (Ann Neurol), IVT minor stroke (Neurology).

Global Burden of Disease

GBD stroke: Lancet Neurology, JAMA Neurology, Nat Commun.

Publications

Selected Publications

Individualized Treatment in DMVO Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Doheim MF, Mohammaden MH, et al.

Annals of Neurology (2026)

First AuthorPMID: 41603297

Direct Transport to a Thrombectomy Center Accelerates Reperfusion Therapies in Nonurban Settings

Bhatt NR, ..., Doheim MF, et al.

J Am Heart Assoc. 2026;15(1):e044213

Association of Anesthesia Strategies with Outcomes in EVT for DMVO: MR CLEAN & Meta-analysis

Doheim MF, Knapen RRMM, et al.

European Stroke Journal (2026)

First AuthorPMID: 41614488

ATLAS-ER: Adjunctive Thrombolytics After Successful Endovascular Reperfusion

Doheim MF, Mohammaden MH, Jumah A, et al.

Ann Neurol. 2025;98(6):1299-1314

First AuthorPMID: 40799167

Direct Endovascular Versus Bridging Therapy in M2 Occlusion: MR CLEAN Registry

Doheim MF, Knapen RRMM, Staals J, et al.

Stroke. 2025;56(10):2866-2878

First AuthorPMID: 40878683

Meta-Analysis of RCTs on IV Thrombolysis in Minor Acute Ischemic Stroke

Doheim MF, Nguyen TN, Xiong Y, et al.

Neurology. 2025;105(3):e213863

First AuthorPMID: 40674672

VERITAS: Endovascular therapy for acute vertebrobasilar occlusion — IPD meta-analysis

Nogueira RG, Jovin TG, et al. (incl. Doheim MF)

The Lancet. 2025;405(10472):61-69

73 citationsPMID: 39674187

IVT Prior to EVT in Basilar Artery Occlusions: Pooled Analysis of Four RCTs

Knapen RRMM, Doheim MF, et al.

Cardiovasc Intervent Radiol. 2025;48(12):1869-1877

Global Burden of Nontraumatic Subarachnoid Hemorrhage: GBD 2021

GBD Collaborators (incl. Doheim MF)

JAMA Neurology. 2025;82(8):765-787

18 citationsPMID: 40406922

Global burden of stroke and its risk factors, 1990–2021: GBD 2021

GBD Collaborators (incl. Doheim MF)

Lancet Neurology. 2024;23(10):973-1003

930 citationsPMID: 39304265

Global burden of disorders affecting the nervous system, 1990–2021: GBD 2021

GBD Collaborators (incl. Doheim MF)

Lancet Neurology. 2024;23(4):344-381

1,566 citationsPMID: 38493795

Mode of Onset Modifies Effect of Time to EVT: DAWN Trial Analysis

Nogueira RG, Doheim MF, Jadhav AP, et al.

Ann Neurol. 2024;96(2):356-364

DMVO Strokes: Understanding the Present and Paving the Way for a Better Future

Nogueira RG, Doheim MF, Al-Bayati AR, et al.

J Stroke. 2024;26(2):190-202

38 citationsPMID: 38836268

Higher Procedural Volumes Associated with Better Outcomes in EVT

Nogueira RG, et al. (incl. Doheim MF)

Ann Neurol. (2023)

From Therapeutic Nihilism to Armamentarium: Meta-analysis of EVT RCTs

Doheim MF, Hagrass AI, et al.

Interventional Neuroradiology (2023)

First AuthorPMID: 37082795

Neurological Events after COVID-19 Vaccines: VAERS Analysis

Frontera JA, Tamborska AA, Doheim MF, et al.

Ann Neurol. 2022;91(6):756-771

123 citationsPMID: 35233819

Direct to Angiosuite vs Conventional Imaging in Suspected LVO: Meta-Analysis

Mohammaden MH, Doheim MF, et al.

Stroke. 2022;53(8):2478-2487

35 citationsPMID: 35593152

Gastrointestinal Congenital Anomalies at 264 Hospitals in 74 Countries

Global PaedSurg (incl. Doheim MF)

The Lancet. 2021;398(10297):325-339

155 citationsPMID: 34270932
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