MD, PhD · Assistant Professor of Neurology (Clinical Research) · Founding Director, NeuroPrecision Lab
Advancing individualized care in acute ischemic stroke through clinical trial evidence, big data analytics, medical device innovation, and artificial intelligence.
I integrate causal inference methodology, machine learning, and clinical trial design to move beyond one-size-fits-all treatment toward individualized therapeutic strategies in acute ischemic stroke.
As Founding Director of NeuroPrecision Lab and Primary Manager of the DUSK Trial, I lead research bridging computational innovation with direct patient care — from counterfactual models published in Annals of Neurology to AI triage platforms across 60 hospitals.
Causal ML and counterfactual estimation for individualized EVT decisions in DMVO and posterior circulation stroke.
AI triage platforms across 60 spokes improving workflow, reducing transfers, and promoting equity.
Primary Manager & Co-PI of the DUSK Trial — a multicenter RCT evaluating thrombectomy for distal medium vessel occlusion stroke.
Two provisional patents: intracranial stent and AI-powered stroke decision support platform.
Landmark meta-analyses in The Lancet (VERITAS), Annals of Neurology (ATLAS-ER), and Neurology.
GBD collaborator: stroke burden in Lancet Neurology, JAMA Neurology, Nature Communications.
Accelerating Reversal and Refining Transfer Are Imperative for Anticoagulation-Associated Intracerebral Hemorrhage
Doheim MF, AlMajali M, Al-Janabi OM.
J Am Heart Assoc. 2026 Feb 12:e047926 · doi: 10.1161/JAHA.125.047926 · PMID: 41676936
Advancing Precision Medicine in Acute Stroke Care: Personalized Treatment Strategies and Outcomes
Doheim MF, Bhatt N, Al-Bayati AR, Baron JC, de Andrade JBC.
Front Med (Lausanne). 2025 Nov 11;12:1718309 · doi: 10.3389/fmed.2025.1718309 · PMID: 41306504; PMCID: PMC12643980
Individualized Treatment in DMVO Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model
Doheim MF, Mohammaden MH, Abdelhamid H, et al.
Annals of Neurology (2026) · PMID: 41603297
ATLAS-ER: Adjunctive Thrombolytics After Successful Endovascular Reperfusion — Meta-Analysis of RCTs
Doheim MF, Mohammaden MH, Jumah A, et al.
Annals of Neurology 2025;98(6):1299-1314 · PMID: 40799167
VERITAS: Endovascular therapy for acute vertebrobasilar occlusion — IPD meta-analysis
Nogueira RG, Jovin TG, et al. (incl. Doheim MF)
The Lancet 2025;405(10472):61-69 · PMID: 39674187
Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion: MR CLEAN Registry
Doheim MF, Knapen RRMM, Staals J, et al.
Stroke 2025;56(10):2866-2878 · PMID: 40878683
Meta-Analysis of RCTs on IV Thrombolysis in Minor Acute Ischemic Stroke
Doheim MF, Nguyen TN, Xiong Y, et al.
Neurology 2025;105(3):e213863 · PMID: 40674672
Open to collaborations in precision stroke medicine, AI in clinical trials, and neurovascular innovation.